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Differential regulation of calcium homeostasis in adenocarcinoma cell line A549 and its Taxol-resistant subclone

1. Drug resistance is a fundamental problem in cancer chemotherapy. Intracellular calcium concentration ([Ca(2+)](i)) may play a role in the development of chemoresistance. We investigated the regulatory role of [Ca(2+)](i) in Taxol resistance in the non-small-cell lung cancer cell line A549 and its...

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Main Authors: Padar, Shanthala, van Breemen, Cornelis, Thomas, David W, Uchizono, James A, Livesey, John C, Rahimian, Roshanak
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574945/
https://ncbi.nlm.nih.gov/pubmed/15066902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705755
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