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Thromboxane receptor stimulation associated with loss of SK(Ca) activity and reduced EDHF responses in the rat isolated mesenteric artery

1. The possibility that thromboxane (TXA(2)) receptor stimulation causes differential block of the SK(Ca) and IK(Ca) channels which underlie EDHF-mediated vascular smooth muscle hyperpolarization and relaxation was investigated in the rat isolated mesenteric artery. 2. Acetylcholine (30 nM–3 μM ACh)...

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Detalhes bibliográficos
Main Authors: Crane, G J, Garland, C J
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574933/
https://ncbi.nlm.nih.gov/pubmed/15051624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705756
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