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The structure of a stable intermediate in the A ↔ B DNA helix transition

The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 Å has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a...

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Main Authors: Ng, Ho-Leung, Kopka, Mary L., Dickerson, Richard E.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC15749/
https://ncbi.nlm.nih.gov/pubmed/10688897
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