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Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea

1. The 5-HT receptor subtype that mediates bronchocontraction and the involvement of neuronal and non-neuronal acetylcholine was assessed in murine isolated tracheae. 2. Atropine (1–10 nM) caused a rightward shift of the methacholine concentration–effect curves (pA(2)=9.0) but reduced the maximum re...

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Hlavní autoři: Moffatt, James D, Cocks, Thomas M, Page, Clive P
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574888/
https://ncbi.nlm.nih.gov/pubmed/15023864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705720
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