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Alpha-1 adrenoceptors: evaluation of receptor subtype-binding kinetics in intact arterial tissues and comparison with membrane binding

1. The binding kinetics of [(3)H]-prazosin were measured using intact segments of rat tail artery (RTA) and thoracic aorta (RAO), and the data were compared with those obtained using a conventional membrane ligand-binding method. 2. In intact RTA and RAO segments, [(3)H]-prazosin bound reversibly in...

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Detalhes bibliográficos
Main Authors: Tanaka, Takashi, Zhang, Li, Suzuki, Fumiko, Muramatsu, Ikunobu
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574210/
https://ncbi.nlm.nih.gov/pubmed/14718262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705627
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