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Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via myenteric neurons and tachykinin NK(2)/NK(3) receptors

1. The ability of calcitonin gene-related peptide (CGRP), to alter the outflow of 5-hydroxytryptamine (5-HT) from the guinea-pig proximal colon, was evaluated using three different isolated preparations: whole colon, mucosa-free muscle layer and submucosa/mucosa preparations. 2. In the presence of t...

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Detalhes bibliográficos
Main Authors: Kojima, Shu-ichi, Ueda, Shuichi, Ikeda, Masashi, Kamikawa, Yuichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574207/
https://ncbi.nlm.nih.gov/pubmed/14718265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705624
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