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Topiramate hyperpolarizes and modulates the slow poststimulus AHP of rat olfactory cortical neurones in vitro
1. The effects of the novel antiepileptic drug topiramate (TPM) were investigated in rat olfactory cortex neurones in vitro using a current/voltage clamp technique. 2. In 80% of recorded cells, bath application of TPM (20 μM) reversibly hyperpolarized and inhibited neuronal repetitive firing by indu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574203/ https://ncbi.nlm.nih.gov/pubmed/14691058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705617 |
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