Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins

1. Matrix metalloproteinase-2 (MMP-2) plays a role in agonist- and tumour cell-induced platelet aggregation (TCIPA). 2. MMP-2 is synthesized as a proenzyme and is activated at the cell surface by membrane type-1 matrix metalloproteinase (MT1-MMP, MMP-14). 3. The significance of tumour cell-associate...

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Autores principales: Alonso-Escolano, David, Strongin, Alex Y, Chung, Ada W, Deryugina, Elena I, Radomski, Marek W
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574193/
https://ncbi.nlm.nih.gov/pubmed/14691052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705606
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