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Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis

1. The contribution of nitric oxide (NO) and peroxynitrite (PN) to inflammation in a zymosan-induced (1 mg, intra-articular, i.art.) rat model of arthritis was assessed by histopathology and by measuring the glycosaminoglycan (GAG) content of the articular cartilage. 2. Progression of the chronic sy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bezerra, Mirna Marques, Brain, Susan D, Greenacre, Stan, Jerônimo, Selma Maria Bezerra, de Melo, Liana Batista, Keeble, Julie, da Rocha, Francisco Airton Castro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574182/
https://ncbi.nlm.nih.gov/pubmed/14662723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705600
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