Ouabain exerts biphasic effects on connexin functionality and expression in vascular smooth muscle cells

1. We have compared the effects of ouabain on the maintenance of gap junctional communication in rat aortic A7r5 smooth muscle cells, monkey COS-1 fibroblasts and human HeLa epithelial cells. 2. Ouabain (1 mM) interrupted dye coupling between confluent A7r5 cells within ∼1 h, and high concentrations...

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Bibliographic Details
Main Authors: Martin, Patricia E M, Hill, Nathan S, Kristensen, Bo, Errington, Rachael J, Griffith, Tudor M
Format: Artigo
Language:Inglês
Published: 2003
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574142/
https://ncbi.nlm.nih.gov/pubmed/14645140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705556
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