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Ouabain exerts biphasic effects on connexin functionality and expression in vascular smooth muscle cells

1. We have compared the effects of ouabain on the maintenance of gap junctional communication in rat aortic A7r5 smooth muscle cells, monkey COS-1 fibroblasts and human HeLa epithelial cells. 2. Ouabain (1 mM) interrupted dye coupling between confluent A7r5 cells within ∼1 h, and high concentrations...

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Detalhes bibliográficos
Main Authors: Martin, Patricia E M, Hill, Nathan S, Kristensen, Bo, Errington, Rachael J, Griffith, Tudor M
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574142/
https://ncbi.nlm.nih.gov/pubmed/14645140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705556
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