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Alkylglycerol opening of the blood–brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries

1. The blood–brain barrier (BBB) represents the major impediment to successful delivery of therapeutic agents to target tissue within the central nervous system. Intracarotid alkylglycerols have been shown to increase the transfer of chemotherapeutics across the BBB. 2. We investigated the spatial d...

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Detalhes bibliográficos
Main Authors: Erdlenbruch, Bernhard, Alipour, Mehrnaz, Fricker, Gert, Miller, David S, Kugler, Wilfried, Eibl, Hansjörg, Lakomek, Max
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574140/
https://ncbi.nlm.nih.gov/pubmed/14597599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705554
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