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Effects of TRA-418, a novel TP-receptor antagonist, and IP-receptor agonist, on human platelet activation and aggregation

1. {4-[2-(1,1-Diphenylethylsulfanyl)-ethyl]-3,4-dihydro-2H-benzo[1,4]oxazin-8-yloxy}-acetic acid N-Methyl-D-glucamine salt (TRA-418) has both thromboxane A(2) (TP)-receptor antagonist and prostacyclin (IP)-receptor agonist properties. The present study examined the advantageous effects of TRA-418 ba...

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Detalhes bibliográficos
Main Authors: Miyamoto, Mitsuko, Yamada, Naohiro, Ikezawa, Shiho, Ohno, Michihiro, Otake, Atsushi, Umemura, Kazuo, Matsushita, Teruo
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574093/
https://ncbi.nlm.nih.gov/pubmed/14504133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705499
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