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Glycosylated human oxyhaemoglobin activates nuclear factor-κB and activator protein-1 in cultured human aortic smooth muscle

1. Diabetic vessels undergo structural changes that are linked to a high incidence of cardiovascular diseases. Reactive oxygen species (ROS) mediate cell signalling in the vasculature, where they can promote cell growth and activate redox-regulated transcription factors, like activator protein-1 (AP...

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Detalhes bibliográficos
Main Authors: Peiró, Concepción, Matesanz, Nuria, Nevado, Julián, Lafuente, Nuria, Cercas, Elena, Azcutia, Verónica, Vallejo, Susana, Rodríguez-Mañas, Leocadio, Sánchez-Ferrer, Carlos F
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574072/
https://ncbi.nlm.nih.gov/pubmed/14504138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705483
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