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Tetrahydrocannabinol-induced neurotoxicity depends on CB(1) receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons
1. Δ(9)-Tetrahydrocannabinol (THC), the main psychoactive ingredient of marijuana, induces apoptosis in cultured cortical neurons. THC exerts its apoptotic effects in cortical neurons by binding to the CB(1) cannabinoid receptor. The CB(1) receptor has been shown to couple to the stress-activated pr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574055/ https://ncbi.nlm.nih.gov/pubmed/14522843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705464 |
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