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Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat

1. The cytokine interleukin-1 (IL-1) has been implicated in ischaemic, excitotoxic and traumatic brain damage in rodents. The naturally occurring IL-1 receptor antagonist (IL-1ra) markedly reduces neuronal injury in these conditions. However, the effects of IL-1ra on focal, transient cerebral ischae...

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Detalhes bibliográficos
Main Authors: Mulcahy, Nicholas J, Ross, Jerard, Rothwell, Nancy J, Loddick, Sarah A
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574053/
https://ncbi.nlm.nih.gov/pubmed/12970087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705462
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