Norcantharidin-induced apoptosis is via the extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase signaling pathways in human hepatoma HepG2 cells

1. Norcantharidin (NCTD) is an anticancer drug routinely used against hepatoma in China. Previously, we reported that NCTD could induce mitotic arrest and apoptosis in human hepatoma HepG2 cells. However, the intracellular signaling pathways involved in NCTD-induced apoptotic cell death are still ob...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Yan-Nian, Cheng, Chi-Chih, Chen, Jung-Chou, Tsauer, Wei, Hsu, Shih-Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
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Reviews
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574052/
https://ncbi.nlm.nih.gov/pubmed/12970086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705461
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