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Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats

1. The regional haemodynamic effects of the putative nNOS inhibitor, S-methyl-L-thiocitrulline (SMTC), were compared with those of the nonselective NOS inhibitor, N(G)-nitro-L-arginine methyl ester (L-NAME), in conscious, male Sprague–Dawley rats. 2. SMTC (0.3 mg kg(−1) bolus) produced a significant...

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Autori principali: Wakefield, Ian D, March, Julie E, Kemp, Philip A, Valentin, Jean-Pierre, Bennett, Terence, Gardiner, Sheila M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573945/
https://ncbi.nlm.nih.gov/pubmed/12871844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705351
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