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Modulation of ATP-induced currents by zinc in acutely isolated hypothalamic neurons of the rat

1. Whole-cell patch-clamp and fast perfusion were used to study the effects of zinc on adenosine 5′-triphosphate (ATP)-induced responses of histaminergic neurons. 2. At 10–30 μM ATP, Zn(2+) had biphasic effects on ATP responses. Zn(2+) at 3–100 μM increased the ATP-induced currents, but inhibited th...

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Autori principali: Vorobjev, Vladimir S, Sharonova, Irina N, Sergeeva, Olga A, Haas, Helmut L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573915/
https://ncbi.nlm.nih.gov/pubmed/12839865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705321
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