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Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis

1. FK506 and cyclosporin A (CsA) are immunosuppressive drugs, that specifically inhibit T-cell activation via calcineurin inhibition. This study was undertaken to investigate whether calcineurin inhibitors exert analgesic actions in rat adjuvant-induced arthritis (AIA), an animal model of rheumatoid...

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Detalhes bibliográficos
Main Authors: Magari, Katsue, Miyata, Susumu, Ohkubo, Yoshitaka, Mutoh, Seitaro, Goto, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573910/
https://ncbi.nlm.nih.gov/pubmed/12839866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705310
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