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Effects of heparin and related molecules upon neutrophil aggregation and elastase release in vitro

1. Neutrophil-derived elastase is an enzyme implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). Heparin inhibits the enzymatic activity of elastase and here we provide evidence for the first time that heparin can inhibit the release of elastase from human neutrophils. 2....

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Detalhes bibliográficos
Main Authors: Brown, Rachel A, Lever, Rebecca, Jones, Neil A, Page, Clive P
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573888/
https://ncbi.nlm.nih.gov/pubmed/12813008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705291
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