Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle

1. In guinea-pig ileal longitudinal muscle, muscarinic partial agonists, 4-(N-[3-chlorophenyl]-carbomoyloxy)-2-butynyl-trimethylammonium (McN-A343) and pilocarpine, each produced parallel increases in tension and cytosolic Ca(2+) concentration ([Ca(2+)]c) with a higher EC(50) than that of the full a...

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Bibliographic Details
Main Authors: Unno, T, Kwon, S-C, Okamoto, H, Irie, Y, Kato, Y, Matsuyama, H, Komori, S
Format: Artigo
Language:Inglês
Published: 2003
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573862/
https://ncbi.nlm.nih.gov/pubmed/12770939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705267
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