Endothelium dysfunction in LDL receptor knockout mice: a role for H(2)O(2)

1. In this study, the role of endogenous H(2)O(2) as an endothelium-dependent relaxant factor was characterised in aortas from C57BL/6J and LDL receptor-deficient mice (LDLR(−/−)). 2. Aortic rings from LDLR(−/−) mice showed impaired endothelium-dependent relaxation to acetylcholine (ACh; 0.001–100 μ...

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Main Authors: Rabelo, Luíza A, Cortes, Steyner F, Alvarez-Leite, Jacqueline I, Lemos, Virgínia S
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573774/
https://ncbi.nlm.nih.gov/pubmed/12711621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705164
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