h5-HT(1B) receptor-mediated constitutive Gα(i3)-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT

1. Serotonin 5-HT(1B) receptors couple to G-proteins of the Gi/o family. However, their activation of specific G-protein subtypes is poorly characterised. Using an innovative antibody capture/guanosine-5′-0-(3-[(35)S]thio)-triphosphate ([(35)S]GTPγS) binding strategy, we characterised Gα(i3) subunit...

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Bibliographic Details
Main Authors: Newman-Tancredi, Adrian, Cussac, Didier, Marini, Laetitia, Touzard, Manuelle, Millan, Mark J
Format: Artigo
Language:Inglês
Published: 2003
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573751/
https://ncbi.nlm.nih.gov/pubmed/12684263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705140
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