Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain

1. The aim of this study was to find taurinergic compounds that do not interact with brain GABA ergic systems. 2. Washed synaptic membranes (SM) from whole rabbit brain were able to bind [(3)H]muscimol. Saturation experiments of the binding of [(3)H]GABA to GABA(B) receptors showed that SM possess t...

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Hlavní autoři: Frosini, Maria, Sesti, Casilde, Dragoni, Stefania, Valoti, Massimo, Palmi, Mitri, Dixon, Henry B F, Machetti, Fabrizio, Sgaragli, Giampietro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573748/
https://ncbi.nlm.nih.gov/pubmed/12684273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705134
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