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Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation

1. Ajoene is a garlic compound with anti-platelet properties and, in addition, was shown to inhibit cholesterol biosynthesis by affecting 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase and late enzymatic steps of the mevalonate (MVA) pathway. 2. MVA constitutes the precursor not only of...

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Hlavní autoři: Ferri, Nicola, Yokoyama, Kohei, Sadilek, Martin, Paoletti, Rodolfo, Apitz-Castro, Rafael, Gelb, Michael H, Corsini, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573737/
https://ncbi.nlm.nih.gov/pubmed/12642382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705126
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