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RSD931, a novel anti-tussive agent acting on airway sensory nerves

1. The anti-tussive effects, of the local anaesthetic, lidocaine and carcainium chloride (RSD931) have been investigated in guinea-pigs and rabbits. 2. Pre-treatment of guinea-pigs with aerosols of lidocaine or RSD931 at 0.1, 1.0 and 10 mg ml(−1) reduced the number of citric acid-induced coughs by 9...

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Bibliografiska uppgifter
Huvudupphovsmän: Adcock, J J, Douglas, G J, Garabette, M, Gascoigne, M, Beatch, G, Walker, M, Page, C P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573683/
https://ncbi.nlm.nih.gov/pubmed/12569065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705056
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