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Attenuation of acute and chronic effects of morphine by the imidazoline receptor ligand 2-(2-benzofuranyl)-2-imidazoline in rat locus coeruleus neurons

1. The aim of this study was to determine if 2-(2-benzofuranyl)-2-imidazoline (2-BFI) interacts with the opioid system in the rat locus coeruleus, using single-unit extracellular recordings. 2. In morphine-dependent rats, acute administration of the selective imidazoline receptor ligands 2-BFI (10 a...

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Bibliographic Details
Main Authors: Ruiz-Durántez, Eduardo, Torrecilla, María, Pineda, Joseba, Ugedo, Luisa
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573679/
https://ncbi.nlm.nih.gov/pubmed/12569074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705052
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