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Interaction between cysteines introduced into each transmembrane domain of the rat P2X(2) receptor

1. ATP-gated ion channels (P2X receptors) contain two hydrophobic segments that are presumed to span the plasma membrane (TM1 and TM2). Pairs of cysteines were introduced by mutagenesis into the rat P2X(2) receptor, one in TM1 one in TM2, at positions where single substitutions have previously been...

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Detalhes bibliográficos
Main Authors: Spelta, Valeria, Jiang, Lin-Hua, Bailey, R Jayne, Surprenant, Annmarie, North, R Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573644/
https://ncbi.nlm.nih.gov/pubmed/12522082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705018
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