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Interaction between cysteines introduced into each transmembrane domain of the rat P2X(2) receptor

1. ATP-gated ion channels (P2X receptors) contain two hydrophobic segments that are presumed to span the plasma membrane (TM1 and TM2). Pairs of cysteines were introduced by mutagenesis into the rat P2X(2) receptor, one in TM1 one in TM2, at positions where single substitutions have previously been...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Spelta, Valeria, Jiang, Lin-Hua, Bailey, R Jayne, Surprenant, Annmarie, North, R Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573644/
https://ncbi.nlm.nih.gov/pubmed/12522082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705018
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