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Unproductive cleavage and the inactivation of protease-activated receptor-1 by trypsin in vascular endothelial cells
1. Using fura-2 fluorometry of [Ca(2+)](i) in response to thrombin, trypsin and protease-activated receptor activating peptides (PAR-APs), we determined whether trypsin cleaves protease-activated receptor 1 (PAR1) and activates it in the endothelial cells of the porcine aortic valves and human umbil...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573634/ https://ncbi.nlm.nih.gov/pubmed/12522081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705008 |
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