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Oxidative and non-oxidative mechanisms of neuronal cell death and apoptosis by L-3,4-dihydroxyphenylalanine (L-DOPA) and dopamine

1. The present study was designed to evaluate the nature of intervening agents in L-DOPA- and dopamine-induced neurotoxicity in Neuro-2A cells. 2. In the absence of cells and in conditions of light protection, at 37°C, L-DOPA or dopamine (1 mM) in culture medium degraded spontaneously in a time-depe...

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Autors principals: Pedrosa, R, Soares-da-Silva, P
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573607/
https://ncbi.nlm.nih.gov/pubmed/12466240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704982
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