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4-aminopyridine- and dendrotoxin-sensitive potassium channels influence excitability of vagal mechano-sensitive endings in guinea-pig oesophagus

1. Distension-sensitive vagal afferent fibres from the guinea-pig oesophagus were recorded extracellularly in vitro. Most recorded units were spontaneously active firing at 3.2±0.3 Hz (n=41, N=41) and had low thresholds (less than 1 mm) to circumferential stretch. Dynamic and adapted phases of stret...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zagorodnyuk, Vladimir P, Chen, Bao Nan, Costa, Marcello, Brookes, Simon J H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573601/
https://ncbi.nlm.nih.gov/pubmed/12466228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704964
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