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Nitric oxide inhibits capacitative Ca(2+) entry by suppression of mitochondrial Ca(2+) handling

1. Nitric oxide (NO) is a key modulator of cellular Ca(2+) signalling and a determinant of mitochondrial function. Here, we demonstrate that NO governs capacitative Ca(2+) entry (CCE) into HEK293 cells by impairment of mitochondrial Ca(2+) handling. 2. Authentic NO as well as the NO donors 1-[2-(car...

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Détails bibliographiques
Auteurs principaux: Thyagarajan, Baskaran, Malli, Roland, Schmidt, Kurt, Graier, Wolfgang F, Groschner, Klaus
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573569/
https://ncbi.nlm.nih.gov/pubmed/12411413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704949
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