Mechanism of lonidamine inhibition of the CFTR chloride channel

1. The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel is blocked by a broad range of organic anionic compounds. Here we investigate the effects of the indazole compound lonidamine on CFTR channels expressed in mammalian cell lines using patch clamp recording. 2. Application...

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Hlavní autoři: Gong, Xiandi, Burbridge, Susan M, Lewis, Angie C, Wong, Patrick Y D, Linsdell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573555/
https://ncbi.nlm.nih.gov/pubmed/12411425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704932
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