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Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine

1. Vascular endothelial growth factor (VEGF) plays an important role in the neovascularization of ischaemic retinal diseases such as proliferative diabetic retinopathy. We determined that bucillamine, an anti-rheumatic drug, inhibits the VEGF production induced by hypoxia in bovine retinal microcapi...

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Detalhes bibliográficos
Main Authors: Koyama, Shinji, Takagi, Hitoshi, Otani, Atsushi, Oh, Hideyasu, Nishimura, Kazuo, Honda, Yoshihito
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573552/
https://ncbi.nlm.nih.gov/pubmed/12411422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704929
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