Gingerols: a novel class of vanilloid receptor (VR1) agonists

1. Gingerols, the pungent constituents of ginger, were synthesized and assessed as agonists of the capsaicin-activated VR1 (vanilloid) receptor. 2. [6]-Gingerol and [8]-gingerol evoked capsaicin-like intracellular Ca(2+) transients and ion currents in cultured DRG neurones. These effects of gingerol...

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Autors principals: Dedov, Vadim N, Tran, Van H, Duke, Colin C, Connor, Mark, Christie, MacDonald J, Mandadi, Sravan, Roufogalis, Basil D
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573550/
https://ncbi.nlm.nih.gov/pubmed/12411409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704925
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