Role of the platelet-activating factor (PAF) receptor during pulmonary infection with gram negative bacteria

1. The lipid mediator PAF plays an important role in the phagocytosis of particles, including bacteria, and consequent production of pro-inflammatory cytokines, such as TNF-α and IL-8. 2. Using a PAF receptor antagonist (UK-74,505) and PAF receptor knock-out mice, we have investigated the relevance...

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Detalhes bibliográficos
Main Authors: Soares, A C, Pinho, V S, Souza, D G, Shimizu, T, Ishii, S, Nicoli, J R, Teixeira, M M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573539/
https://ncbi.nlm.nih.gov/pubmed/12381675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704918
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