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Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL-60 cells: antagonism of hCCR1 activation by MIP-1β

1. C-C chemokine receptor-1 (CCR1) has been implicated in mediating a variety of inflammatory conditions including multiple sclerosis and organ rejection. Although originally referred to as the MIP-1α/RANTES receptor, CCR1 is quite promiscuous and can be activated by numerous chemokines. 2. We used...

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Detalhes bibliográficos
Main Authors: Chou, Chuan-Chu, Fine, Jay S, Pugliese-Sivo, Catherine, Gonsiorek, Waldemar, Davies, Liza, Deno, Gregory, Petro, Mary, Schwarz, Martin, Zavodny, Paul J, Hipkin, R William
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573530/
https://ncbi.nlm.nih.gov/pubmed/12381680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704907
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