Gene expressions in Jurkat cells poisoned by a sulphur mustard vesicant and the induction of apoptosis

1. The sulphur mustard vesicant 2-chloroethylethyl sulphide (CEES) induced apoptosis in Jurkat cells. 2. Akt (PKB), a pivotal protein kinase which can block apoptosis and promotes cell survival, was identified to be chiefly down-regulated in a dose-dependent manner following CEES treatment. Function...

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Detalhes bibliográficos
Main Authors: Zhang, Peng, Ng, Patrick, Caridha, Diana, Leach, Richard A, Asher, Ludmila V, Novak, Mark J, Smith, William J, Zeichner, Steven L, Chiang, Peter K
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573481/
https://ncbi.nlm.nih.gov/pubmed/12208782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704856
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