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Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test

1. Orexin-A and orexin-B (also known as hypocretin-1 and hypocretin-2) are hypothalamic peptides and regulate feeding behaviour, energy metabolism and the sleep-wake cycle. Orexin-A binds equally to both orexin-1 and orexin-2 receptors, while orexin-B has a preferential affinity for orexin-2 recepto...

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Detalhes bibliográficos
Main Authors: Yamamoto, Tatsuo, Nozaki-Taguchi, Natsuko, Chiba, Tanemichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573477/
https://ncbi.nlm.nih.gov/pubmed/12208773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704851
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