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Characterization of GABA(A) receptor ligands in the rat cortical wedge preparation: evidence for action at extrasynaptic receptors?

1. GABA(A) receptor agonists have previously been characterized at human GABA(A) receptors expressed in Xenopus oocytes. The correlation between these data and functional in vivo data of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) has shown that THIP is 100 fold more potent in clinical stu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ebert, B, i Storustovu, S, Mortensen, M, Frølund, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573472/
https://ncbi.nlm.nih.gov/pubmed/12183325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704846
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