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Induction of mitochondrial permeability transition by auranofin, a Gold(I)-phosphine derivative

1. Gold(I)-thiolate drugs are compounds that specifically interact with thiol and/or selenol groups and are essentially utilized in the treatment of rheumatoid arthritis. 2. Considering the importance of thiol groups in regulating mitochondrial membrane permeability, the effects of auranofin (S-trie...

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Detalhes bibliográficos
Main Authors: Rigobello, Maria Pia, Scutari, Guido, Boscolo, Rita, Bindoli, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573451/
https://ncbi.nlm.nih.gov/pubmed/12163349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704823
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