Pharmacological characterization of a novel cell line expressing human α(4)β(3)δ GABA(A) receptors

1. The pharmacology of the stable cell line expressing human α(4)β(3)δ GABA(A) receptor was investigated using whole-cell patch-clamp techniques. 2. α(4)β(3)δ receptors exhibited increased sensitivity to GABA when compared to α(4)β(3)γ(2) receptors, with EC(50)'s of 0.50 (0.46, 0.53) μM and 2.6...

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Main Authors: Brown, N, Kerby, J, Bonnert, T P, Whiting, P J, Wafford, K A
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573424/
https://ncbi.nlm.nih.gov/pubmed/12145096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704795
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