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Airway function, oedema, cell infiltration and nitric oxide generation in conscious ozone-exposed guinea-pigs: effects of dexamethasone and rolipram

1. The effects of ozone inhalation (90 min, 2.15±0.05 p.p.m.) and their modification by dexamethasone (20 mg kg(−1)) or the phosphodiesterase-4 inhibitor, rolipram (1 mg kg(−1)), administered (i.p.) 24 and 0.5 h before and 24 h after ozone exposure were examined in conscious guinea-pigs. 2. Ozone ca...

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Detalhes bibliográficos
Main Authors: Toward, Toby J, Broadley, Kenneth J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573394/
https://ncbi.nlm.nih.gov/pubmed/12086983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704764
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