YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells

1. YC-1, an activator of soluble guanylate cyclase (sGC), has been shown to increase the intracellular cGMP concentration. This study was designed to investigate the signaling pathway involved in the YC-1-induced COX-2 expression in A549 cells. 2. YC-1 caused a concentration- and time-dependent incr...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chang, Ming-Shyan, Lee, Wen-Sen, Teng, Che-Ming, Lee, Horng-Mo, Sheu, Joen-Rong, Hsiao, George, Lin, Chien-Huang
Format: Artigo
Langue:Inglês
Publié: 2002
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573389/
https://ncbi.nlm.nih.gov/pubmed/12055134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704777
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