An investigation of the effects of zaprinast, a PDE inhibitor, on the nitrergic control of the urethra in anaesthetized female rats

1. The effects of L-NAME and zaprinast were investigated (i.v.) on reflex-evoked changes in bladder and urethral pressures in urethane-anaesthetized female rats. 2. L-NAME attenuated reflex-evoked urethral relaxations (65±10%), while zaprinast potentiated these responses (68±24%). L-NAME and zaprina...

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Bibliografiset tiedot
Päätekijät: Wibberley, Alexandra, Nunn, Philip A, Naylor, Alasdair M, Ramage, Andrew G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2002
Aiheet:
Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573365/
https://ncbi.nlm.nih.gov/pubmed/12023943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704735
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