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A direct inhibitory action of prostaglandins upon ACTH secretion at the late stages of the secretory pathway of AtT-20 cells

1. The mouse AtT-20/D16-16 anterior pituitary tumour cell line was used as a model system for the study of the effects of prostaglandins upon the late stages of the adrenocorticotrophin (ACTH) secretory pathway. 2. Calcium (1 nM – 100 μM), guanosine-5′-O-(3-thiotriphosphate) (GTP-γ-S) (1 – 100 μM) a...

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Detalhes bibliográficos
Main Authors: Wilson, Mary L, Guild, Simon B
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573316/
https://ncbi.nlm.nih.gov/pubmed/11959787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704652
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