Rolipram inhibits leukocyte-endothelial cell interactions in vivo through P- and E-selectin downregulation

1. Rolipram, a selective phosphodiesterase (PDE) type 4 inhibitor, was used to characterize leukocyte recruitment mechanisms in models of acute and subacute inflammation. Intravital microscopy within the rat mesenteric microcirculation was employed. 2. Mesentery superfusion with PAF (0.1 μM) induced...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sanz, María-Jesús, Alvarez, Angeles, Piqueras, Laura, Cerdá, Miguel, Issekutz, Andrew C, Lobb, Roy R, Cortijo, Julio, Morcillo, Esteban J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573309/
https://ncbi.nlm.nih.gov/pubmed/11959789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704644
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados