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Pharmacologic and autoradiographic evidence for an up-regulation of kinin B(2) receptors in the spinal cord of spontaneously hypertensive rats

1. The effects of intrathecally (i.t.) injected kinin B(1) and B(2) receptor agonists and antagonists were measured on mean arterial pressure (MAP) and heart rate (HR) of conscious unrestrained spontaneously hypertensive rats (SHR of 16 weeks old) and age-matched normotensive Wistar Kyoto (WKY). Qua...

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Autori principali: Cloutier, Frank, Buck, Hudson de Sousa, Ongali, Brice, Couture, Réjean
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573297/
https://ncbi.nlm.nih.gov/pubmed/11934804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704632
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