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Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats

1. The contribution of the local vascular production of angiotensin-(1-7) [Ang-(1-7)] to the control of α-adrenergic-induced contractions in the aorta of Sprague-Dawley (SD) and TGR(mRen-2)27 [mRen-2] rats was studied. 2. In mRen-2 rats, contractile responses to phenylephrine were diminished as comp...

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Detalhes bibliográficos
Main Authors: Lemos, Virgínia S, Côrtes, Steyner F, Silva, Denise M R, Campagnole-Santos, Maria J, Santos, Robson A S
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573295/
https://ncbi.nlm.nih.gov/pubmed/11934815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704630
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