Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins

1. The present study was performed to evaluate and compare the ability of human MDR1-, and rat Mdr1b- and Mdr2-P-glycoproteins to transport hydrophilic monoquaternary drugs. Transport studies were performed with plasma membrane vesicles isolated from MDR1-, Mdr1b-, or Mdr2-overexpressing insect cell...

Full description

Saved in:
Bibliographic Details
Main Authors: Hooiveld, Guido J E J, Heegsma, Janette, Montfoort, Jessica E van, Jansen, Peter L M, Meijer, Dirk K F, Müller, Michael
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573286/
https://ncbi.nlm.nih.gov/pubmed/11934808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704620
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items